Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Four agents — acarbose (ACA), 17-α-estradiol (EST), nordihydroguaiaretic acid (NDGA), and methylene blue (MB) — were evaluated for lifespan effects in genetically heterogeneous mice tested at three sites. Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lif...

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Detaylı Bibliyografya
Asıl Yazarlar: Harrison, David E, Strong, Randy, Allison, David B, Ames, Bruce N, Astle, Clinton M, Atamna, Hani, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin A, Nadon, Nancy L, Nelson, James F, Pletcher, Scott, Simpkins, James W, Smith, Daniel, Wilkinson, J Erby, Miller, Richard A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954939/
https://ncbi.nlm.nih.gov/pubmed/24245565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12170
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