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Deletion of α-subunit exon 11 of the epithelial Na(+) channel reveals a regulatory module

Epithelial Na(+) channel (ENaC) subunits (α, β, and γ) found in functional complexes are translated from mature mRNAs that are similarly processed by the inclusion of 13 canonical exons. We examined whether individual exons 3–12, encoding the large extracellular domain, are required for functional c...

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Autors principals: Chen, Jingxin, Kleyman, Thomas R., Sheng, Shaohu
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949035/
https://ncbi.nlm.nih.gov/pubmed/24402098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00587.2013
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