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MEK targeting in N-RAS mutated metastatic melanoma
BACKGROUND: Gain of function mutations in B-RAF and N-RAS occur frequently in melanoma, leading to mitogen activating protein kinase (MAPK) pathway activation, and this pathway is the target of drugs in development. Our purpose was to study clinical characteristics of patients with mutations in this...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945937/ https://ncbi.nlm.nih.gov/pubmed/24588908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-45 |
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