Phosphatidylinositol-3-Kinase as a Therapeutic Target in Melanoma

PURPOSE: Phosphatidylinositol-3 kinases (PI3K) are critical for malignant cellular processes including growth, proliferation, and survival, and are targets of drugs in clinical development. We assessed expression of PI3K in melanomas and nevi, and studied associations between PI3K pathway members an...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Aziz, Saadia A., Davies, Michael, Pick, Elah, Zito, Christopher, Jilaveanu, Lucia, Camp, Robert L., Rimm, David L., Kluger, Yuval, Kluger, Harriet M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431617/
https://ncbi.nlm.nih.gov/pubmed/19383818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2768
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