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Drug targets and predictive biomarkers in the management of metastatic melanoma

Melanoma is the leading cause of fatal skin cancer, and in the past few decades, there has been an increase in the incidence of and mortality from metastatic melanoma. Until recently, the therapeutic options for treatment of metastatic melanoma were limited. The approval of ipilimumab (an anti-CTLA-...

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Bibliographic Details
Main Authors: Thumar, Jaykumar, Giesen, Eva, Kluger, Harriet M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513235/
https://ncbi.nlm.nih.gov/pubmed/23226069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S25100
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