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Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures

The PKD1 gene is essential for a number of biological functions, and its loss-of-function causes autosomal dominant polycystic kidney disease (ADPKD). The gene is developmentally regulated and believed to play an essential role in renal development. Previous studies have shown that manipulating muri...

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Autors principals: Rowe, Isaline, Chiaravalli, Marco, Piontek, Klaus B., Germino, Gregory G., Boletta, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945815/
https://ncbi.nlm.nih.gov/pubmed/24472557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.01.068
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