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Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures
The PKD1 gene is essential for a number of biological functions, and its loss-of-function causes autosomal dominant polycystic kidney disease (ADPKD). The gene is developmentally regulated and believed to play an essential role in renal development. Previous studies have shown that manipulating muri...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945815/ https://ncbi.nlm.nih.gov/pubmed/24472557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.01.068 |
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