Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury

Mononuclear phagocyte recognition of apoptotic cells triggering suppressive cytokine signaling is a key event in inflammation resolution from injury. Mice deficient in thrombospondin-1 (thbs1(−/−)), an extracellular matrix glycoprotein that bridges cell-cell interactions, are prone to LPS-induced lu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhao, Yani, Xiong, Zeyu, Lechner, Elizabeth J., Klenotic, Philip A., Hamburg, Brian J., Hulver, Mei, Khare, Anupriya, Oriss, Timothy, Mangalmurti, Nilam, Chan, Yvonne, Zhang, Yingze, Ross, Mark A., Stolz, Donna B., Rosengart, Matthew R., Pilewski, Joseph, Ray, Prabir, Ray, Anuradha, Silverstein, Roy L., Lee, Janet S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945733/
https://ncbi.nlm.nih.gov/pubmed/24045574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.63
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