Duffy Antigen Receptor for Chemokines Mediates Chemokine Endocytosis through a Macropinocytosis-Like Process in Endothelial Cells

BACKGROUND: The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells. Recent evidence suggests that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recr...

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Main Authors: Zhao, Yani, Mangalmurti, Nilam S., Xiong, Zeyu, Prakash, Bharat, Guo, Fengli, Stolz, Donna B., Lee, Janet S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246497/
https://ncbi.nlm.nih.gov/pubmed/22216333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029624
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