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The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity
The Duffy antigen receptor for chemokines (DARC) belongs to a family of ‘silent’ heptahelical chemokine receptors that do not couple to G proteins and fail to transmit measurable intracellular signals. DARC binds most inflammatory chemokines and is prominently expressed on venular endothelial cells,...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205989/ https://ncbi.nlm.nih.gov/pubmed/19060902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1675 |
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