The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity

The Duffy antigen receptor for chemokines (DARC) belongs to a family of ‘silent’ heptahelical chemokine receptors that do not couple to G proteins and fail to transmit measurable intracellular signals. DARC binds most inflammatory chemokines and is prominently expressed on venular endothelial cells,...

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Autori principali: Pruenster, Monika, Mudde, Liesbeth, Bombosi, Paula, Dimitrova, Svetla, Zsak, Marion, Middleton, Jim, Richmond, Ann, Graham, Gerard J, Segerer, Stephan, Nibbs, Robert J B, Rot, Antal
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205989/
https://ncbi.nlm.nih.gov/pubmed/19060902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1675
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