A mouse model for the cystic fibrosis delta F508 mutation.

Most cystic fibrosis (CF) patients produce a mutant form (delta F508) of the cystic fibrosis transmembrane conductance regulator (CFTR), which is not properly processed in normal cells but is active as a chloride channel in several experimental systems. We used a double homologous recombination (�...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: van Doorninck, J H, French, P J, Verbeek, E, Peters, R H, Morreau, H, Bijman, J, Scholte, B J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00119.x
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