A mouse model for the cystic fibrosis delta F508 mutation.

Most cystic fibrosis (CF) patients produce a mutant form (delta F508) of the cystic fibrosis transmembrane conductance regulator (CFTR), which is not properly processed in normal cells but is active as a chloride channel in several experimental systems. We used a double homologous recombination (�...

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Hauptverfasser: van Doorninck, J H, French, P J, Verbeek, E, Peters, R H, Morreau, H, Bijman, J, Scholte, B J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC394531/
https://ncbi.nlm.nih.gov/pubmed/7556083
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