A mouse model for the cystic fibrosis delta F508 mutation.
Most cystic fibrosis (CF) patients produce a mutant form (delta F508) of the cystic fibrosis transmembrane conductance regulator (CFTR), which is not properly processed in normal cells but is active as a chloride channel in several experimental systems. We used a double homologous recombination ('Hi...
Uloženo v:
| Vydáno v: | EMBO J |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00119.x |
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