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Rare variants in BMP2 and BMP4 found in otosclerosis patients reduce Smad signaling
HYPOTHESIS: Genetic variation in BMP2 and BMP4 found in otosclerosis patients result in altered Smad signaling. BACKGROUND: Otosclerosis is a common form of adult-onset conductive hearing loss resulting from abnormal bone remodeling of the bony labyrinth that surrounds the inner ear. Both genetic an...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945298/ https://ncbi.nlm.nih.gov/pubmed/24492129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0000000000000244 |
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