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Identification of phosphatases for Smad in the BMP/DPP pathway

Phosphorylation of the SSXS motif of Smads is critical in activating the transforming growth factor β (TGF-β) and bone morphogenetic protein (BMP) pathways. However, the phosphatase(s) involved in dephosphorylating and hence inactivating Smads remained elusive. Through RNA interference (RNAi)-based...

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Autori principali: Chen, Hong B., Shen, Jiali, Ip, Y. Tony, Xu, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413280/
https://ncbi.nlm.nih.gov/pubmed/16510868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1384706
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