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Association of Bone Morphogenetic Proteins With Otosclerosis

We studied the role of polymorphisms in 13 candidate genes on the risk of otosclerosis in two large independent case-control sets. We found significant association in both populations with BMP2 and BMP4, implicating these two genes in the pathogenesis of this disease. INTRODUCTION: Otosclerosis is a...

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Detalhes bibliográficos
Main Authors: Schrauwen, Isabelle, Thys, Melissa, Vanderstraeten, Kathleen, Fransen, Erik, Dieltjens, Nele, Huyghe, Jeroen R, Ealy, Megan, Claustres, Mireille, Cremers, Cor RWJ, Dhooge, Ingeborg, Declau, Frank, Van de Heyning, Paul, Vincent, Robert, Somers, Thomas, Offeciers, Erwin, Smith, Richard JH, Van Camp, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669162/
https://ncbi.nlm.nih.gov/pubmed/18021008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.071112
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