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Abasic and Oxidized Abasic Site Reactivity in DNA: Enzyme Inhibition, Cross-linking, and Nucleosome Catalyzed Reactions
[Image: see text] Abasic lesions are a family of DNA modifications that lack Watson-Crick bases. The parent member of this family, the apurinic/apyrimidinic lesion (AP), occurs as an intermediate during DNA repair, following nucleobase alkylation, and from random hydrolysis of native nucleotides. In...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944396/ https://ncbi.nlm.nih.gov/pubmed/24369694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar400229d |
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