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Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides
The C4'-oxidized abasic site (C4-AP) forms two types of interstrand cross-links with the adjacent nucleotides in DNA. Previous experiments revealed that dG does not react with the lesion and that formation of one type of cross-link is catalyzed by the opposing dA. Iso-guanosine•dC and 2-aminopu...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177026/ https://ncbi.nlm.nih.gov/pubmed/21903404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.08.024 |
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