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Correlation of Thermal Stability and Structural Distortion of DNA Interstrand Cross-Links Produced from Oxidized Abasic Sites with Their Selective Formation and Repair
C4′-oxidized (C4-AP) and C5′-oxidized abasic sites (DOB) that are produced following abstraction of a hydrogen atom from the DNA backbone reversibly form cross-links selectively with dA opposite a 3′-adjacent nucleotide, despite the comparable proximity of an opposing dA. A previous report on UvrABC...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623589/ https://ncbi.nlm.nih.gov/pubmed/26426430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00860 |
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