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Synthesis of Cross-Linked DNA Containing Oxidized Abasic Site Analogues

[Image: see text] DNA interstrand cross-links are an important family of DNA damage that block replication and transcription. Recently, it was discovered that oxidized abasic sites react with the opposing strand of DNA to produce interstrand cross-links. Some of the cross-links between 2′-deoxyadeno...

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Detalhes bibliográficos
Main Authors: Ghosh, Souradyuti, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084848/
https://ncbi.nlm.nih.gov/pubmed/24949656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500944g
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