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Akt and mTOR mediate programmed necrosis in neurons

Necroptosis is a newly described form of regulated necrosis that contributes to neuronal death in experimental models of stroke and brain trauma. Although much work has been done elucidating initiating mechanisms, signaling events governing necroptosis remain largely unexplored. Akt is known to inhi...

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書誌詳細
主要な著者: Liu, Q, Qiu, J, Liang, M, Golinski, J, van Leyen, K, Jung, J E, You, Z, Lo, E H, Degterev, A, Whalen, M J
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944276/
https://ncbi.nlm.nih.gov/pubmed/24577082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.69
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