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Akt and mTOR mediate programmed necrosis in neurons

Necroptosis is a newly described form of regulated necrosis that contributes to neuronal death in experimental models of stroke and brain trauma. Although much work has been done elucidating initiating mechanisms, signaling events governing necroptosis remain largely unexplored. Akt is known to inhi...

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Detalhes bibliográficos
Main Authors: Liu, Q, Qiu, J, Liang, M, Golinski, J, van Leyen, K, Jung, J E, You, Z, Lo, E H, Degterev, A, Whalen, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944276/
https://ncbi.nlm.nih.gov/pubmed/24577082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.69
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