Phosphorylated AKT inhibits the apoptosis induced by DRAM-mediated mitophagy in hepatocellular carcinoma by preventing the translocation of DRAM to mitochondria

Increasing autophagy is beneficial for curing hepatocellular carcinoma (HCC). Damage-regulated autophagy modulator (DRAM) was recently reported to induce apoptosis by mediating autophagy. However, the effects of DRAM-mediated autophagy on apoptosis in HCC cells remain unclear. In this study, normal...

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Detalhes bibliográficos
Main Authors: Liu, K, Shi, Y, Guo, X H, Ouyang, Y B, Wang, S S, Liu, D J, Wang, A N, Li, N, Chen, D X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944266/
https://ncbi.nlm.nih.gov/pubmed/24556693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.51
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