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Insulin stimulates Akt translocation to mitochondria: Implications on dysregulation of mitochondrial oxidative phosphorylation in diabetic myocardium

Mitochondrial oxidative phosphorylation is the major source of energy in cardiac muscle. In the streptozotocin-induced diabetic (STZ-DM) mice, myocardial oxidative phosphorylation was perturbated and oxidative phosphorylation complex V (ATP synthase) activity was significantly reduced. To determine...

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Autors principals: Yang, Jia-Ying, Yeh, Hung-Yin, Lin, Kevin, Wang, Ping H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872534/
https://ncbi.nlm.nih.gov/pubmed/19249309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.02.015
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