A Novel Pleckstrin Homology Domain-containing Protein Enhances Insulin-stimulated Akt Phosphorylation and GLUT4 Translocation in Adipocytes

Protein kinase B/Akt protein kinases control an array of diverse functions, including cell growth, survival, proliferation, and metabolism. We report here the identification of pleckstrin homology-like domain family B member 1 (PHLDB1) as an insulin-responsive protein that enhances Akt activation. P...

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Hlavní autoři: Zhou, Qiong L., Jiang, Zhen Y., Mabardy, Allan S., Del Campo, Claudia M., Lambright, David G., Holik, John, Fogarty, Kevin E., Straubhaar, Juerg, Nicoloro, Sarah, Chawla, Anil, Czech, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934625/
https://ncbi.nlm.nih.gov/pubmed/20587420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146886
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