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Neutrophil Activation During Acetaminophen Hepatotoxicity and Repair in Mice and Humans

Following acetaminophen (APAP) overdose there is an inflammatory response triggered by release of cellular contents from necrotic hepatocytes into systemic circulation which initiates the recruitment of neutrophils into the liver. It has been demonstrated that neutrophils do not contribute to APAP-i...

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Detalhes bibliográficos
Main Authors: Williams, C. David, Bajt, Mary Lynn, Sharpe, Matthew R., McGill, Mitchell R., Farhood, Anwar, Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941640/
https://ncbi.nlm.nih.gov/pubmed/24440789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.01.004
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