ACETAMINOPHEN-INDUCED HEPATIC NEUTROPHIL ACCUMULATION AND INFLAMMATORY LIVER INJURY IN CD18-DEFICIENT MICE

BACKGROUND: Acetaminophen (APAP) hepatotoxicity is currently the most frequent cause of acute liver failure in the US and many European countries. Although intracellular signaling mechanisms are critical for hepatocellular injury, a contribution of inflammatory cells, especially neutrophils, has bee...

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Gepubliceerd in:Liver Int
Hoofdauteurs: Williams, C. David, Bajt, Mary Lynn, Farhood, Anwar, Jaeschke, Hartmut
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278356/
https://ncbi.nlm.nih.gov/pubmed/20500806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2010.02284.x
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