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ACETAMINOPHEN-INDUCED HEPATIC NEUTROPHIL ACCUMULATION AND INFLAMMATORY LIVER INJURY IN CD18-DEFICIENT MICE

BACKGROUND: Acetaminophen (APAP) hepatotoxicity is currently the most frequent cause of acute liver failure in the US and many European countries. Although intracellular signaling mechanisms are critical for hepatocellular injury, a contribution of inflammatory cells, especially neutrophils, has bee...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Williams, C. David, Bajt, Mary Lynn, Farhood, Anwar, Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278356/
https://ncbi.nlm.nih.gov/pubmed/20500806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2010.02284.x
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