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Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia

Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...

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Autors principals: Guise, Christopher P., Mowday, Alexandra M., Ashoorzadeh, Amir, Yuan, Ran, Lin, Wan-Hua, Wu, Dong-Hai, Smaill, Jeff B., Patterson, Adam V., Ding, Ke
Format: Artigo
Idioma:Inglês
Publicat: Sun Yat-sen University Cancer Center 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://ncbi.nlm.nih.gov/pubmed/23845143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10285
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