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Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia

Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...

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Détails bibliographiques
Auteurs principaux: Guise, Christopher P., Mowday, Alexandra M., Ashoorzadeh, Amir, Yuan, Ran, Lin, Wan-Hua, Wu, Dong-Hai, Smaill, Jeff B., Patterson, Adam V., Ding, Ke
Format: Artigo
Langue:Inglês
Publié: Sun Yat-sen University Cancer Center 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://ncbi.nlm.nih.gov/pubmed/23845143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10285
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