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Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia

Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...

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Detalhes bibliográficos
Main Authors: Guise, Christopher P., Mowday, Alexandra M., Ashoorzadeh, Amir, Yuan, Ran, Lin, Wan-Hua, Wu, Dong-Hai, Smaill, Jeff B., Patterson, Adam V., Ding, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://ncbi.nlm.nih.gov/pubmed/23845143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10285
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