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Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia

Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...

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Detalles Bibliográficos
Main Authors: Guise, Christopher P., Mowday, Alexandra M., Ashoorzadeh, Amir, Yuan, Ran, Lin, Wan-Hua, Wu, Dong-Hai, Smaill, Jeff B., Patterson, Adam V., Ding, Ke
Formato: Artigo
Idioma:Inglês
Publicado: Sun Yat-sen University Cancer Center 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://ncbi.nlm.nih.gov/pubmed/23845143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.012.10285
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