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Tumour Hypoxia-Mediated Immunosuppression: Mechanisms and Therapeutic Approaches to Improve Cancer Immunotherapy

The magnitude of the host immune response can be regulated by either stimulatory or inhibitory immune checkpoint molecules. Receptor-ligand binding between inhibitory molecules is often exploited by tumours to suppress anti-tumour immune responses. Immune checkpoint inhibitors that block these inhib...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Fu, Zhe, Mowday, Alexandra M., Smaill, Jeff B., Hermans, Ian F., Patterson, Adam V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146304/
https://ncbi.nlm.nih.gov/pubmed/33923305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051006
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