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Bioreductively Activatable Prodrug Conjugates of Phenstatin Designed to Target Tumor Hypoxia
A variety of solid tumor cancers contain significant regions of hypoxia, which provide unique challenges for targeting by potent anticancer agents. Bioreductively activatable prodrug conjugates (BAPCs) represent a promising strategy for therapeutic intervention. BAPCs are designed to be biologically...
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| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319644/ https://ncbi.nlm.nih.gov/pubmed/28007448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.11.093 |
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