Contributions of KRAS and RAL in Non-Small Cell Lung Cancer growth and progression

INTRODUCTION: KRAS mutations are poor prognostic markers for patients with non-small cell lung cancer (NSCLC). RALA and RALB GTPases lie downstream of RAS and are implicated in RAS mediated tumorigenesis. However, their biological or prognostic role in the context of KRAS mutation in NSCLC is unclea...

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Detalhes bibliográficos
Main Authors: Guin, Sunny, Ru, Yuanbin, Wynes, Murry W., Mishra, Rangnath, Lu, Xian, Owens, Charles, Barόn, Anna E., Vasu, Vihas T., Hirsch, Fred R., Kern, Jeffrey A., Theodorescu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934792/
https://ncbi.nlm.nih.gov/pubmed/24389431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000007
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