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Contributions of KRAS and RAL in Non-Small Cell Lung Cancer growth and progression

INTRODUCTION: KRAS mutations are poor prognostic markers for patients with non-small cell lung cancer (NSCLC). RALA and RALB GTPases lie downstream of RAS and are implicated in RAS mediated tumorigenesis. However, their biological or prognostic role in the context of KRAS mutation in NSCLC is unclea...

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Bibliografiske detaljer
Main Authors: Guin, Sunny, Ru, Yuanbin, Wynes, Murry W., Mishra, Rangnath, Lu, Xian, Owens, Charles, Barόn, Anna E., Vasu, Vihas T., Hirsch, Fred R., Kern, Jeffrey A., Theodorescu, Dan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934792/
https://ncbi.nlm.nih.gov/pubmed/24389431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000007
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