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CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

BACKGROUND: Loss of Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) drives rapid proliferation of bladder cancer cells by upregulating Hyaluronic acid(HA) Synthase (HAS2) mediated HA synthesis. However the role of HA receptors CD44 and Hyaluronan Mediated Motility Receptor (RHAMM) in re...

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Publicat a:BMC Cancer
Autors principals: Oldenburg, Darby, Ru, Yuanbin, Weinhaus, Benjamin, Cash, Steve, Theodorescu, Dan, Guin, Sunny
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011830/
https://ncbi.nlm.nih.gov/pubmed/27595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2756-5
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