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CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

BACKGROUND: Loss of Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) drives rapid proliferation of bladder cancer cells by upregulating Hyaluronic acid(HA) Synthase (HAS2) mediated HA synthesis. However the role of HA receptors CD44 and Hyaluronan Mediated Motility Receptor (RHAMM) in re...

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Bibliografiset tiedot
Julkaisussa:BMC Cancer
Päätekijät: Oldenburg, Darby, Ru, Yuanbin, Weinhaus, Benjamin, Cash, Steve, Theodorescu, Dan, Guin, Sunny
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011830/
https://ncbi.nlm.nih.gov/pubmed/27595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2756-5
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