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CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

BACKGROUND: Loss of Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) drives rapid proliferation of bladder cancer cells by upregulating Hyaluronic acid(HA) Synthase (HAS2) mediated HA synthesis. However the role of HA receptors CD44 and Hyaluronan Mediated Motility Receptor (RHAMM) in re...

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Podrobná bibliografie
Vydáno v:BMC Cancer
Hlavní autoři: Oldenburg, Darby, Ru, Yuanbin, Weinhaus, Benjamin, Cash, Steve, Theodorescu, Dan, Guin, Sunny
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011830/
https://ncbi.nlm.nih.gov/pubmed/27595989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2756-5
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