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The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear
HIV-1 Nef is an accessory protein responsible for inactivation of a number of host cell proteins essential for anti-viral immune responses. In most cases, Nef binds to the target protein and directs it to a degradation pathway. Our previous studies demonstrated that Nef impairs activity of the cellu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934640/ https://ncbi.nlm.nih.gov/pubmed/24406162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.12.141 |
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