136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin

HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways. Nef is also responsible for downregulation of cellular cholesterol transporter ABCA1, and this effect cont...

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Bibliographische Detailangaben
Hauptverfasser: Jennelle, Lucas, Hunegnaw, Ruth, Dubrovsky, Larisa, Pushkarsky, Tatiana, Fitzgerald, Michael L., Sviridov, Dmitri, Bukrinsky*, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
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Abstract
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.qai.0000446716.85972.b0
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