HIV-1 Protein Nef Inhibits Activity of ATP-binding Cassette Transporter A1 by Targeting Endoplasmic Reticulum Chaperone Calnexin

HIV-infected patients are at increased risk of developing atherosclerosis, in part due to an altered high density lipoprotein profile exacerbated by down-modulation and impairment of ATP-binding cassette transporter A1 (ABCA1) activity by the HIV-1 protein Nef. However, the mechanisms of this Nef ef...

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Autori principali: Jennelle, Lucas, Hunegnaw, Ruth, Dubrovsky, Larisa, Pushkarsky, Tatiana, Fitzgerald, Michael L., Sviridov, Dmitri, Popratiloff, Anastas, Brichacek, Beda, Bukrinsky, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200247/
https://ncbi.nlm.nih.gov/pubmed/25170080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.583591
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