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Interaction between HIV-1 Nef and calnexin: from modeling to small molecule inhibitors reversing HIV-induced lipid accumulation
OBJECTIVE: HIV-infected patients are at an increased risk of developing atherosclerosis, in part due to downmodulation and functional impairment of ATP-Binding Cassette A1 (ABCA1) cholesterol transporter by the HIV-1 protein Nef. The mechanism of this effect involves Nef interacting with an endoplas...
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| Опубликовано в: : | Arterioscler Thromb Vasc Biol |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5040351/ https://ncbi.nlm.nih.gov/pubmed/27470515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307997 |
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