HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux

HIV infection, through the actions of viral accessory protein Nef, impairs activity of cholesterol transporter ABCA1, inhibiting cholesterol efflux from macrophages and elevating the risk of atherosclerosis. Nef also induces lipid raft formation. In this study, we demonstrate that these activities a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cui, Huanhuan L., Grant, Angela, Mukhamedova, Nigora, Pushkarsky, Tatiana, Jennelle, Lucas, Dubrovsky, Larisa, Gaus, Katharina, Fitzgerald, Michael L., Sviridov, Dmitri, Bukrinsky, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307646/
https://ncbi.nlm.nih.gov/pubmed/22262807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M023119
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados