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Mutation of the ABCA1 C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation
HIV-1 infection and antiretroviral therapy associate with a dyslipidemia marked by low HDL levels and increased cardiovascular disease, but it is obscure whether virion replication plays a causative role in these changes. The HIV-1 Nef protein can impair ABCA1 cholesterol efflux from macrophages, a...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943568/ https://ncbi.nlm.nih.gov/pubmed/20731376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100466q |
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