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136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin
HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways. Nef is also responsible for downregulation of cellular cholesterol transporter ABCA1, and this effect cont...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
JAIDS Journal of Acquired Immune Deficiency Syndromes
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149662/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.qai.0000446716.85972.b0 |
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