The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear

HIV-1 Nef is an accessory protein responsible for inactivation of a number of host cell proteins essential for anti-viral immune responses. In most cases, Nef binds to the target protein and directs it to a degradation pathway. Our previous studies demonstrated that Nef impairs activity of the cellu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jacob, Daria, Hunegnaw, Ruth, Sabyrzyanova, Tatyana A., Pushkarsky, Tatiana, Chekhov, Vladimir O., Adzhubei, Alexei A., Kalebina, Tatyana S., Bukrinsky, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934640/
https://ncbi.nlm.nih.gov/pubmed/24406162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.12.141
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg