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PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells
A single nucleotide polymorphism in the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22), that encodes the Lyp tyrosine phosphatase LypR620W, has been linked to a number of autoimmune diseases including type I diabetes, rheumatoid arthritis and systemic lupus erythematosus. Studies in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933017/ https://ncbi.nlm.nih.gov/pubmed/24453256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302418 |
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