Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers

The monoclonal anti-CD20 antibody rituximab (RTX) depletes B cells in the treatment of lymphoma and autoimmune disease, and contributes to alloantibody reduction in transplantation across immunologic barriers. The effects of RTX on T cells are less well described. T-follicular helper (Tfh) cells pro...

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Autores principales: Wallin, Elizabeth F., Jolly, Elaine C., Suchánek, Ondřej, Bradley, J. Andrew, Espéli, Marion, Jayne, David R. W., Linterman, Michelle A., Smith, Kenneth G. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208282/
https://ncbi.nlm.nih.gov/pubmed/25224411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-585976
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