Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal center response

Follicular helper (T(FH)) cells provide crucial signals to germinal center B cells undergoing somatic hypermutation and selection that results in affinity maturation. Tight control of T(FH) numbers maintains self-tolerance. We describe a population of Foxp3(+)Blimp-1(+)CD4(+) T cells constituting 10...

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Autors principals: Linterman, Michelle A., Pierson, Wim, Lee, Sau K., Kallies, Axel, Kawamoto, Shimpei, Rayner, Tim F., Srivastava, Monika, Divekar, Devina P., Beaton, Laura, Hogan, Jennifer J., Fagarasan, Sidonia, Liston, Adrian, Smith, Kenneth G. C., Vinuesa, Carola G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182542/
https://ncbi.nlm.nih.gov/pubmed/21785433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2425
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