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Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal center response
Follicular helper (T(FH)) cells provide crucial signals to germinal center B cells undergoing somatic hypermutation and selection that results in affinity maturation. Tight control of T(FH) numbers maintains self-tolerance. We describe a population of Foxp3(+)Blimp-1(+)CD4(+) T cells constituting 10...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182542/ https://ncbi.nlm.nih.gov/pubmed/21785433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2425 |
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