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HIV and T follicular helper cells: a dangerous relationship

HIV infection leads to progressive destruction of infected CD4 T cells, hypergammaglobulinemia, and loss of memory B cells. Germinal centers, which are key to memory B cell formation and protective antibody responses, are major HIV reservoirs in which the virus replicates within T follicular helper...

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Detalhes bibliográficos
Autor principal: Vinuesa, Carola G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428103/
https://ncbi.nlm.nih.gov/pubmed/22922252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65175
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