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Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity
Follicular helper T (Tfh) cells select mutated B cells in germinal centres, which can then differentiate into long-lived high affinity memory B cells and plasma cells. Tfh cells are regulated by a unique molecular programme orchestrated by the transcriptional repressor Bcl6. This transcription facto...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002912/ https://ncbi.nlm.nih.gov/pubmed/20364160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.18 |
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