Follicular helper T cells are required for systemic autoimmunity

Production of high-affinity pathogenic autoantibodies appears to be central to the pathogenesis of lupus. Because normal high-affinity antibodies arise from germinal centers (GCs), aberrant selection of GC B cells, caused by either failure of negative selection or enhanced positive selection by foll...

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Xehetasun bibliografikoak
Egile Nagusiak: Linterman, Michelle A., Rigby, Robert J., Wong, Raphael. K., Yu, Di, Brink, Robert, Cannons, Jennifer L., Schwartzberg, Pamela L., Cook, Matthew C., Walters, Giles D., Vinuesa, Carola G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699132/
https://ncbi.nlm.nih.gov/pubmed/19221396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081886
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