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Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling

Effective humoral immunity depends on the support of B cell responses by T-follicular helper (Tfh) cells. Whilst it has been proposed that Tfh cell differentiation requires T-B interactions, the relative contribution of specific populations of Ag presenting cells remains unknown. We employed three i...

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Bibliografiska uppgifter
Huvudupphovsmän: Deenick, Elissa K., Chan, Anna, Ma, Cindy S., Gatto, Dominique, Schwartzberg, Pamela L, Brink, Robert, Tangye, Stuart G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433066/
https://ncbi.nlm.nih.gov/pubmed/20691615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.07.015
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